Fostering Intrapreneurship through the Implementation of Internal Corporate Accelerators

Today’s markets are characterized by fast and radical changes, posing an essential challenge to established companies. Startups, yet, seem to be more capable in developing radical innovations to succeed in those volatile markets. Thus, established companies started to experiment with various approaches to implement startup-like structures in their organization. Internal corporate accelerators (ICAs) are a novel form of corporate venturing, aiming to foster bottom-up innovations through intrapreneurship. However, ICAs still lack empirical investigations. This work contributes to a deeper understanding of the interface between the ICA and the core organization and the respective support activities (resource access and support services) that create an innovation-supportive work environment for the intrapreneurial team. The results of this qualitative study, comprising 12 interviews with ICA teams out of two German high-tech companies, show that the resources provided by ICAs differ from the support activities of external accelerators. Further, the study shows that some resources show both supportive as well as obstructive potential for the intrapreneurial teams within the ICA

Rapid detection by hydrops panel of Noonan syndrome with PTPN11 mutation (p.Thr73Ile) and persistent thrombocytopenia

Background: Nonimmune hydrops fetalis (NIHF) is still a challenging diagnosis. The differential diagnosis is extensive and the success of identifying a cause depends on the thoroughness of efforts to establish a diagnosis. For the early diagnosis of NIHF, a virtual gene panel diagnostic tool was developed. The female premature baby in question was delivered via emergency cesarean at 30 1 weeks of gestational age (GA) due to rapidly developing NIHF to a healthy mother. The family history was noncontributory. Methods DNA of the family was extracted and sequenced by the virtual hydrops panel with whole-exome sequencing. Results: The hydrops panel revealed Noonan syndrome (NS) with a germline mutation in PTPN11 c.218C>T (p.Thr73Ile). Conclusion: The diagnosis of our patient was rapidly confirmed by the hydrops panel. The variant of c.218C>T (p.Thr73Ile) has not yet been described in literature relating to NIHF. Only a few case reports of this variant are known. This particular mutation is associated with Noonan syndrome, congenital heart defect and persistent thrombocytopenia. Few reveal juvenile myelomonocytic leukemia

Bispectral index monitoring during cardiopulmonary resuscitation repeated twice within 8 days in the same patient: a case report

Research on cardiac resuscitation has led to various changes in the techniques and drug administration involved in modern advanced life support. Besides improving primary cardiac survival, interest is increasingly focused on a favourable neurological outcome. However, until now there has been no on-site equipment to support the clinical observations of the cardiopulmonary resuscitation (CPR) team. Bispectral index (BIS) monitoring has been used for avoiding awareness during anaesthesia for many years. We report a case of a 68-year-old patient suffering twice from cardiac arrest due to thromboembolism within a few days. While the first cardiac resuscitation was survived without neurological consequences, the patient died after the second event. Both resuscitation events were monitored using the BIS. We discuss the course of BIS values and their possible contribution to the prediction of outcome

Software Startups -- A Research Agenda

Software startup companies develop innovative, software-intensive products within limited time frames and with few resources, searching for sustainable and scalable business models. Software startups are quite distinct from traditional mature software companies, but also from micro-, small-, and medium-sized enterprises, introducing new challenges relevant for software engineering research. This paper's research agenda focuses on software engineering in startups, identifying, in particular, 70+ research questions in the areas of supporting startup engineering activities, startup evolution models and patterns, ecosystems and innovation hubs, human aspects in software startups, applying startup concepts in non-startup environments, and methodologies and theories for startup research. We connect and motivate this research agenda with past studies in software startup research, while pointing out possible future directions. While all authors of this research agenda have their main background in Software Engineering or Computer Science, their interest in software startups broadens the perspective to the challenges, but also to the opportunities that emerge from multi-disciplinary research. Our audience is therefore primarily software engineering researchers, even though we aim at stimulating collaborations and research that crosses disciplinary boundaries. We believe that with this research agenda we cover a wide spectrum of the software startup industry current needs

Understanding the heterogeneity of corporate entrepreneurship programs

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of working.Corporate entrepreneurship (CE) programs are often used by established companies to address these innovation and transformation challenges. In general, they are understood as formalized entrepreneurial activities to (1) support internal corporate ventures or (2) work with external startups. The organizational design and value creation of CE programs exhibit a high degree of heterogeneity. On the one hand, this heterogeneity makes CE programs a valuable management tool that can be used for many purposes. On the other hand, it can be seen as a reason for the current challenges that companies experience in effectively using and managing CE programs.By systematically analyzing 54 different cases in established companies in Germany, Switzerland, and Austria, this study contributes to a better understanding of the heterogeneity of CE programs. The taxonomic approach provides clearly defined types of CE programs that are distinguished according to their organizational design and the outputs they generate

The corporate entrepreneur

Corporate entrepreneurship is one tool for established companies to strengthen their capabilities for strategic renewal and innovativeness. The question, however, which factors are influencing the success of a corporate entrepreneurship initiative requires further attention. The corporate entrepreneur who is acting as both the leader of embedded entrepreneurial teams and linking pin to the corporate, is providing one possible perspective. Based on 6 interviews conducted in 6 German organizations this study contributes to the understanding of the role of the corporate entrepreneur and how this role can be distinguished from other roles in the context of innovation

Strengthening Organizational Ambidexterity through Corporate Entrepreneurship Activities

In today's volatile world, established companies must be capable of optimizing their core business with incremental innovations while simultaneously developing discontinuous innovations to maintain their long-term competitiveness. Balancing both is a major challenge for companies, since different types of innovation require different organizational structures, operational modes and management styles. Established companies tend to excel in improving their current business through incremental innovations which are closely related to their current knowledge base and competencies. However, this often goes hand in hand with challenges in the exploration of knowledge that is new to the company and that is essential for the development of discontinuous innovations. In this respect, the concept of corporate entrepreneurship is recognized as a way to strengthen the exploration of new knowledge and to support the development of discontinuous innovation. For managing corporate entrepreneurship more effectively, it is crucial to understand which types of knowledge can be created through corporate entrepreneurship and which organizational designs are more suited to gain certain types of knowledge. To answer these questions, this study analyzed 23 semi-structured interviews conducted with established companies that are running such entrepreneurial activities. The results show (1) that three general types of knowledge can be explored through corporate entrepreneurship and (2) that some organizational designs are more suited to explore certain knowledge types than others are

Towards an effective management of corporate entrepreneurship activities

Corporate entrepreneurship (CE) is experiencing continuously increasing interest from scholars and practitioners. One reason for this seems to be rooted in the organizational structures of established companies, which are cumbersome for implementing organizational agility and for developing radical innovations. In view of the advancing digitalization, however, exactly this is required in order to be successful in the long-term. CE is a promising managerial tool that offers a wide range of options to pursue the creation of new businesses and to support the companies' transformation in order to adapt to changes in the environment. Even though CE offers a broad range of opportunities, the effective management is a challenge. One reason for this is the ambiguity when it comes to the differences between the various CE forms and the objectives that can be achieved by those. This study, which is based on 13 in-depth interviews from eight high-tech companies, contributes to a better understanding of CE by offering a first harmonized set of CE objectives that is suitable to compare and differentiate across the different forms. In addition to that, three CE types, offering a new perspective on how to differentiate CE forms, are identified and give implications for a more effective management

Clarifying the roles in corporate entrepreneurship

Corporate entrepreneurship (CE) supports the strategic renewal of established companies. Corporate venturing represents one key concept of CE that supports companies to strengthen their innovation capabilities. For the successful implementation of corporate ventures dual structures are recommended. The question, how the interface should be designed, plays a crucial role. Although it seems to be an important factor, this aspect requires further attention. One relevant element of the interface design are the different roles of the individuals that are interacting within the interface. This study is based on nine interviews that are representing six internal corporate ventures within one large German corporate from the ICT sector. The results that were mirrored with short case studies of 25 additional companies of the data sample, contribute to a better understanding of the interface design by adding insights about roles in corporate entrepreneurship. This deeper understanding about roles allows to draw conclusions on the interface design from a structural point of view